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Description
Patients who stop semaglutide often regain weight

Greig, Email: [email protected]

It is now appreciated that multiple regions within the hypothalamus, brainstem, and beyond, transduce pharmacological GLP-1R-dependent signals in the brain to reduce food intake, enabling weight loss with chronic administration of GLP-1RA (1)
J Family Med Prim Care 10(12):4418 Prasad-Reddy L, Isaacs D (2015) A clinical review of GLP-1 receptor agonists: efficacy and safety in diabetes and beyond
Major cardiovascular outcome trials, including LEADER, SUSTAIN-6, and REWIND, followed patients for several years
