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The primary outcome was change in HbA1c from randomisation to the end of treatment, secondary outcomes included body weight change

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Best GLP-1 Weight Loss Drugs (2026 Comparison Guide) Retatrutide vs Tirzepatide vs Semaglutide: evidence-based insights into results, side effects, costs, and which GLP-1 works best for weight loss

Diarrhea affects up to 25% of people taking Zepbound or tirzepatide
