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REAL-WORLD EVIDENCE ON GLP-1 RAs AND LIVER OUTCOMES Beyond randomized controlled trials, emerging real-world data from large observational cohorts and healthcare databases provide important insights into the long-term effectiveness and safety of GLP-1 RAs in patients with MASLD and type 2 diabetes

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A fresh analysis of the clinical and financial implications of comprehensive coverage in Medicare of GLP-1s for all current FDA indications (type 2 diabetes, obesity, heart disease and metabolic-associated steatohepatitis) offers some hope for long-term cost savings

Zhang, J., Cai, W., Liu, D., Zheng, N., Wang, Y., Qiu, F., Zheng, H., Gan, H., Huang, Y., Zhou, Y., Yu, M., Xiong, S., Luo, G., Guo, J., Zhu, L., Zhang, Y., Ke, H., Liu, Y., Huang, G., Yu, C., Xu, J

This robust pipeline includes drugs that not only target diabetes but also address obesity, recognizing the close link between the two conditions