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These variable responses are consistent with GI adverse reactions documented in the SmPCs for approved GLP-1-based medicines (see, for example, the EMC SmPCs for Wegovy and Mounjaro)

Some people experience weight gain when taking antidepressants, while others may lose weight

Always discuss off-label use risks and benefits with your provider

Lammel S, Lim BK, Ran C, Huang KW, Betley MJ, Tye KM, et al

doi: 10.1002/prp2.867 [DOI] [PMC free article] [PubMed] [Google Scholar] 93.Markham A, Elkinson S
