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doi: 10.2337/db12-1686 67 ChakravarthyHGuXEngeMDaiXWangYDamondNet al

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This benefit appeared independent of weight loss, suggesting direct cardiovascular protective effects from GLP-1 receptor activation

Thirdly, our results revealed the potential impact of the duration of tirzepatide treatment on the development of gallbladder or biliary disease, providing valuable insights into the time-dependent effects and considerations for the safe use of this drug