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Semaglutide GLP-1 is not intended for use in individuals with a BMI below 27 kg/m, as its safety and effectiveness in this population have not been established

The combined effect on gastric emptying could increase gastrointestinal side effects, and there is no clinical data on the safety of combining GLP-1 Complete specifically with semaglutide or tirzepatide

DOI: 10.1016/j.clnu.2023.06.027 Gualdiero, P., Ferrara, L., Ferrara, E., et al

In 2017, the Food and Drug Administration approved Ozempic to treat Type 2 diabetes, but people have also used the drug off-label to lose weight