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Future randomised controlled trials should specifically evaluate the effectiveness of novel AOMs for long-term weight management in older adults with obesity, carefully considering the impact on body composition and functional ability, as well as health economics.

By combining the activities of GLP-1 and E2, we envisioned synergistic insulinotropic activities of these molecules on -cells

If you've been trying to lose weight while breastfeeding, I feel your struggle

But we don't have clean human data on that arc yet

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