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Metabolism 103 , 154031 (2020)
For patients with diabetes, dehydration poses additional risks by potentially affecting kidney function and blood glucose stability

The weight loss from these medications is substantial

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Guidelines provided by KDIGO similarly recommend SGLT2i for people with an eGFR of 30 ml/min/1.73 m 2 due to the vascular and renal benefit, despite its modest effect on glucose control [2]