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This widespread receptor distribution has prompted investigation into potential pleiotropic effects, including anti-inflammatory properties that may contribute to their broader clinical benefits in cardiometabolic disease
Berberine offers modest blood sugar and metabolic support, which supplement companies market as 'GLP-1 support.' However, it does not signal fullness to your brain or suppress appetite like actual GLP-1 hormone does
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Hjerpsted JB, Flint A, Brooks A, Axelsen MB, Kvist T, Blundell J

In rare instances, there were reports that it triggered anxiety, agitation, and depression
