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The secondary aim is to avoid 'additional blows' leading to MASH and acute liver failure and to reduce hepatic fat deposition in patients (234)

As the drug manufacturers Novo Nordisk and Eli Lilly have made exceedingly clear, these medicines are intended as long-term commitments, like medication for high blood pressure

MCP-1, monocyte chemotactic protein 1

The medication is also available in combination with topiramate, called Qsymia, which is approved for chronic weight management

Jung J-H, Yang Y, Kim Y (2025) Hypoxia-induced SREBP1-mediated lipogenesis and autophagy promote cell survival via fatty acid oxidation in breast cancer cells