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Giacosa A, Guido D, Grassi M, et al
Pancreatic Function Enhancement: GLP-1 receptor agonists augment glucose-dependent insulin secretion from pancreatic beta cells while suppressing inappropriate glucagon release from pancreatic alpha cells, supporting more stable blood glucose levels throughout the day and reducing postprandial glucose spikes
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These data suggest that glucagon agonism provides additional liver fat reducing efficacy beyond what is expected from weight loss alone
