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The effect on stroke is remarkable (and was significant in the trials of both semaglutide and dulaglutide), amounting to an 18% risk reduction, also because the other class of new antidiabetic agents with cardiovascular benefits, the SGLT2-inhibitors, show no a similar effect on stroke (but do have a significant effect on heart failure) [24]

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The room was comfortable, with snacks and TV and the chairs Were super cozy with a nice soft blanket

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GLP-1 is secreted in response to carbohydrate, fat, and protein ingestion

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doi: 10.1002/oby.22051

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Septerna has developed a native complex platform that can reconstitute the GLP-1 receptor within an artificial lipid bilayer, complexed with combinations of drug and internal cell signalling molecules, which replicates the dynamics of the signalling process at scale

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