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Saxenda Patient Information Leaflet
40 The high production of acetate was reported to promote glucose-stimulated insulin secretion (GSIS), pancreatic -cell activity, and obesity by activating the parasympathetic nervous system
In these cells, P450c17 was localized in pre- and post-synaptic locations and in the endoplasmic reticulum by immunoelectron microscope analysis [127]
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Despite these promising findings, several barriers and limitations temper their clinical translation
