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Given that the half-life of SGLT2 inhibitors varies from 11 to 13 hours, it seems reasonable to withhold these medications for three days (or five half-lives) before elective surgery

The therapeutic efficacy of GLP-1 is well established (3-5), and epigenetic modulation to amplify GLP-1 receptor (GLP-1R) action has been advocated as an option for the long-term glycemic control and reduction of obesity (6)

In patients with obesity undergoing sleeve gastrectomy, liraglutide has been explored for preoperative management, showing more pronounced effects in females by reducing inflammation and adhesion formation (63)

Other side effects shared in these reviews include heart palpitations, sweating, nausea, shortness of breath, and fatigue