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Researchers emphasize the urgent need for vigilance among prescribers, especially as access to GLP-1s expands

doi: 10.15314/TJSE.201439613 100

It is important to understand that whilst Wegovy frequently causes digestive symptoms, there is no evidence establishing that Wegovy directly causes irritable bowel syndrome (IBS)

For context, Hims has continued offering compounded semaglutide after the FDA declared there was no longer a shortage of the brand-name version (meaning: this regulatory exemption no longer applies)

The observed changes in plasma alanine and glucagon concentrations with survodutide but not placebo or semaglutide indicate target engagement at both the GCGR and the GLP-1R, highlighting that survodutide is a GCGR/GLP-1R dual agonist and its effects are exerted at both receptors