glp 1 mechanism of action diagram Glucagon-like peptide-1 Mechanism of action of GLP-1
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During the process of ER stress, UPR sensors separate from chaperone proteins, such as GRP78 and PDI, and then become phosphorylated, which activates CHOP and apoptotic proteins, such as caspase-12, to induce apoptosis 41
Merhi, Z
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