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Duration of benefit also differs: phentermine effects diminish after stopping, whereas GLP-1 weight loss persists longer when maintained

Figure 1 Schematic representation of GLP-1 receptor (GLP-1R) signaling pathways and their metabolic effects

Ozempic, victoza, trulicity and more have gained widespread popularity over the last several years
In the UK, the Medicines and Healthcare products Regulatory Agency (MHRA) has licensed specific GLP-1 medications for use only in people who are obese, overweight with related health problems, or have type 2 diabetes

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