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Injection Site Reactions Frequency: 8% of trial participants Onset: Within 30 minutes of injection Duration: 24-48 hours typically Severity: Usually mild and self-limiting Injection site reactions are less common with retatrutide than many other peptides, likely due to its weekly dosing schedule allowing more recovery time between injections

Other common clinical features include heart defects, seizures, and behavioral issues, such as ASD or repetitive behaviors behaviors (Deimling et al., 2017

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