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Protein concentrations were measured using the Bradford assay (Bio-Rad)
Despite this, it is thought that this new generation of therapeutics represents a historical inflection point in the advancement for improving obesity and related chronic metabolic diseases
The safety of ingested caffeine: A comprehensive review
These findings are further supported by another sub-analysis of SURMOUNT1, which reported a 33.9% (8.2% for placebo) reduction in fat mass and a 10.9% (2.6% for placebo) reduction in lean mass by week 72, with approximately 75% of weight loss attributable to fat mass, consistent across clinically relevant subgroups [68]
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