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Description
A switch from semaglutide to tirzepatide does not guarantee fewer GI symptoms

Reta is an amino acid-based synthetic peptide polymer and completely lacks a steroid ring structure

Furthermore, GLP-1 analogs improved plasma insulin levels, HOMA-IR, cholesterol levels, and markers of liver damage (AST and ALT), as well as reduced liver hypertrophy

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GPs can refer patients to tier 3 or tier 4 specialist weight management services, and the NIHR 'Be Part of Research' portal (bepartofresearch.nihr.ac.uk) provides a searchable database of UK clinical trials, including those in obesity and metabolic disease
