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Description

Potential mechanisms of interaction between GLP-1RAs and AITD Weight Loss and Adipose Tissue Immunology Adipose tissue is increasingly recognized as an active immunologic organ that contributes to systemic inflammation and autoimmunity through secretion of adipokines and pro-inflammatory cytokines [33]

Bowel obstructions were reported in 0.8% of Saxenda users, versus 0.17% for Contrave

Animal models of colitis have demonstrated that GLP-1 receptor activation may reduce intestinal inflammation through multiple mechanisms, including modulation of pro-inflammatory cytokines such as tumor necrosis factor-alpha (TNF-) and interleukin-6 (IL-6), enhancement of intestinal barrier function, and reduction of oxidative stress