obesity treatment with bariatric surgery vs glp-1 receptor agonists Medication vs. for Weight Loss: Options Matter The Evolution of Metabolic-Bariatric Surgery

Participants in key studies achieved average weight reductions that significantly exceeded those seen with placebo, alongside improvements in cardiometabolic markers

Total caloric intake should not drop below 1,200 calories per day for women or 1,500 calories per day for men for extended periods

This tachyphylaxis occurs with continuous infusion of GLP-1 (154, 157), long acting GLP-1RAs (156), or tirzepatide (151)

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2014Effects of the once-weekly glucagon-like peptide-1 receptor agonist dulaglutide on ambulatory blood pressure and heart rate in patients with type 2 diabetes mellitus