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Compounded semaglutide is a customized medication, not a generic, though it uses the same active ingredient

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N Engl J Med 387(3):205216 Jastreboff AM, le Roux CW, Stefanski A, Aronne LJ, Halpern B, Wharton S, Wilding JPH, Perreault L, Zhang S, Battula R, Bunck MC, Ahmad NN, Jouravskaya I (2025) SURMOUNT-1 investigators

In such cases, do not use the pen, consult your pharmacist for replacement advice, and consider reporting suspected quality defects via the MHRA Yellow Card scheme