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Description
Ann Intern Med (2005) 142(7):54759.10.7326/0003-4819-142-7-200504050-00013 8 SantryHPGillenDLLauderdaleDS

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Who Should Avoid or Proceed with Caution Active, severe Crohn's disease with ongoing inflammation, strictures, or recent hospitalization generally warrants deferral of GLP-1 therapy until disease remission is achieved

While these medications work through separate pathways, their effects can overlap, particularly regarding appetite suppression and cardiovascular stimulation

Typical Treatment Timelines in 2025 Initial Phase (36 months) Goal: Establish dose tolerance and begin weight reduction
