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For people who need clinically proven interventions for obesity or metabolic disease, prescription medications remain the gold standard with the strongest evidence base

This review examines metabolic adaptations during GLP-1RA therapy and their implications for nutritional and redox homeostasis

Other important contributing factors are eating disorders and depression, which are more common in patients with T1D compared to the overall population ( Figure 1 Obesity increases the risk of obesity-related as well as diabetes-related complications in patients with T1D, including micro- and macrovascular complications, various types of cancer, and overall mortality ( Figure 1 )

Locomotor activity was measured using horizontal infrared beams in the operant chambers (Med-Associates, Georgia, VT, USA)

doi: 10.1159/000518849 36 37 PapamargaritisDle RouxCW