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Triple-Hormone-Receptor Agonist Retatrutide for Obesity A Phase 2 Trial Patient-friendly explanation of emerging weight-loss peptides FDAs Concerns with Unapproved GLP-1 Drugs Used for Weight Loss Real people, REAL RESULTS

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JAMA, 324 (21), 2186-2197

In vivo evidence of the role of GLP-1/GLP-1R is from Glp-1r / mice, which exhibited an increased number of osteoclasts accompanied by greater bone resorption activity and increased expression of osteoclast-related genes