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A history of neuropathy, ophthalmopathy, nephropathy and cardiovascular disease at baseline was reported in 11%, 16%, 7% and 0.5% respectively

Early doses are designed to introduce the medication gently, not to deliver full appetite suppression

Preliminary findings suggest that these drugs may have even more unexpected off-label uses, such as helping to reduce alcohol use disorder (AUD), reduce high blood pressure (hypertension), and provide defense against heart disease and even dementia

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While they can deliver powerful benefits glucose control, heart and kidney protection, and even weight loss - drug makers have either stopped or refrained from starting additional clinical trials, leaving regulators without the data needed to approve use in type 1