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But Id be remiss if I didnt discuss the relationship to inflammation (independent of causing leaky gut, too!)

Eat less, move more, have discipline

Cardiometabolic benefits: At 48 weeks, improvements included triglyceride reductions up to 40.6% and apoC-III reductions of 38%, along with substantial weight loss (24%) Post-hoc analysis uncovered reductions in albuminuria (3037%) and increased eGFR (8.5 mL/min/1.73 m), suggesting potential kidney-protective effects TRIUMPH-3 and TRIUMPH-OUTCOMES are ongoing Phase 3 studies targeting Cardiovascular safety and outcomes and Renal function in obese individuals with ASCVD or CKD Future with Other GLP-1 and GIP Analogues (Poly-agonists) The development of multi-receptor agonists like retatrutide is the next-generation leap beyond GLP-1 monotherapy, holding potential efficacy comparable to bariatric surgery with fewer GI limitations

Endocrinology (1996) 137(7):296878.10.1210/endo.137.7.8770921 50 YustaBBaggioLLKoehlerJHollandDCaoXPinnellLJet alGLP-1R agonists modulate enteric immune responses through the intestinal intraepithelial lymphocyte GLP-1R

This equals 0.7-0.8g of protein per pound if you are not familiar with kilo measurements