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On their risk tolerance

Specifically: Monitor routinely muscle strength and function amino-acid profiles short half-life proteins emerging resilience markers (e.g., GDF-15) Mitigate proactively adequate protein intake (1.21.5 g/kg/day) resistance or mixed exercise consider adjuncts that preserve muscle mass identify early biomarker patterns of ERM These steps do not contradict the use of GLP-1RAsthey optimize it

SELECT and SUSTAIN-6 showed real outcomes

Side effects are most common during titration

Patients who are still actively losing weight may not get the benefits and aesthetic results they want from a premature lift or other contouring procedure