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(B) Semaglutide, as a GLP-1 analog, can directly act on fat cells, increase the expression of thermogenic genes for browning phenotype maintenance, improve the expression of uncoupling protein 1 (UCP1), mitochondrial biosynthesis, and thermogenic marker, or promote fatty browning through nitric oxide synthase (NOS), neuropeptides (NPs), sirtuin 1 (STRT1), signal transducer and activator of transcription 3 (STAT3), and bone morphogenetic protein 4 (BMP4) signaling

Pemp, Berthold (Department of Ophthalmology, Medical University of Vienna)

I switched from Athletic Greens to the Previnex Optimal Health Pack a couple months ago

But the real reason Akkermansia matters for this product is a protein it secretes called P9