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Description
You can read the full article at A Novel Glucagon-like Peptide-1 (GLP-1)/Glucagon Hybrid Peptide with Triple-acting Agonist Activity at Glucose-dependent Insulinotropic Polypeptide, GLP-1, and Glucagon Receptors and Therapeutic Potential in High Fat-fed Mice PMC (nih.gov)

In the GI tract, they slow stomach emptying and small-bowel transit, a major reason they reduce post-meal sugar spikes and contribute to feelings of fullness

Gastrointestinal side effects (nausea, vomiting, diarrhea) occur in 3045% of patients during dose escalation and typically resolve within 48 weeks when titration protocols are followed correctly

A Randomized, Controlled Trial of 3.0 mg of Liraglutide in Weight Management
One hypothesis is that this phenomenon is caused by the elevated postprandial GLP-1 and consequently insulin levels after RYGB
