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53,54 Therefore, compounds concerning epigenetic targets, such as lysine methyltransferase (KMT), histone lysine demethylase (KDM), histone acetyltransferase (HAT), bromodomain and extra-terminal (BET), histone deacetylase (HDAC) or DNA methyltransferase (DNMT), have entered clinical trials
US state-level prevalence of adult obesity by race and ethnicity from 1990 to 2022 and forecasted to 2035, JAMA
It also suppresses systemic inflammation and exerts a regulatory effect on the gut-brain-heart axis 60
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