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Description
GLP-1 activates the GLP-1R to stimulate adenylate cyclase (AC), increasing intracellular levels of cyclic AMP (cAMP) (Sandoval and DAlessio, 2015)

At 17 I was diagnosed with PCOS and honestly was never given a great explanation for really what that means

A full certainty of evidence table is presented in Supplementary Table S2
Be cautious about taking dietary supplements if you are pregnant or nursing

In particular GLP-2 is important for overall gut health, so if you lower natural GLP-1 production you also make your gut less healthy
