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Subgroup analysis of patients with3% weight loss revealed superior HbA1c improvements in the semaglutide group

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Potential for Durable Weight Retention After GLP-1 Therapy Discontinuation Despite Prolonged Drug Cessation: Across both cohorts, discontinuation at day 0 after a full year of continuous therapy shows that, on average, most patients do not experience clinically meaningful weight regain over prolonged follow-up, despite assured non-prescription of GLP-1 therapy for at least the first 6 months post-cessation and continued monitoring out to 18 months