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Some individuals also experience tachyphylaxisa gradual decline in medication effectiveness over weeks or monthsdue to receptor downregulation

J., Rubin, R

If experiencing signs of dehydrationincluding dizziness, weakness, or decreased urine outputdonors should notify staff immediately during donation or seek appropriate medical care for severe or persistent symptoms

They are the main contractile nonproliferative apparatus needed for mixing and propelling the intraluminal contents, however they can exhibit phenotypic switching, hyperplasia, hypertrophy, and altered contractile behavior upon intestinal pathologies

2007;292:E28191