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Methods In this retrospective cohort study, 125 474 adults with overweight or obesity newly initiated treatment with a dual-labeled GLP-1 RA (liraglutide, semaglutide, or tirzepatide) between January 1, 2018, and December 31, 2023, with a baseline body mass index of 27 or more, an available weight measurement within 60 days before initiation, and regular care in the year before initiation were identified using electronic health record data from a collective of US health care systems

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Hypoglycaemia is only a potential issue if GLP-1 analogues are combined with a sulfonylurea or insulin

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T.DifferdingM

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How Does Semaglutide Work for Weight Loss

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There was no effect of food on Cmax and Tmax of metformin

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