long term effects of glp 1 agonists GLP-1RA Essentials in Gastroenterology: Side Effect Management, Precautions for Endoscopy and Applications for Gastrointestinal Disease Treatment Part 2 of a 3-Part

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8,9,30 The agents used in these trials, including higher-dose semaglutide (2.4 mg) and the dual GLP-1/GIP receptor agonist tirzepatide, have demonstrated compelling benefits

These are very effective medications as a tool to lose weight, he said

This makes it a particularly logical addition for people transitioning off tirzepatide or semaglutide who want to maintain some GLP-1 pathway support without the full potency and cost of injectable GLP-1 agonists

Another mechanism is that GLP-1 may reduce RGC loss indirectly by preventing Mller cell gliosis