sublingual delivery glp-1 receptor agonists Optimized of dual fatty acid–conjugated agonist TE-8105 produces durable efficacy in diabetic mice BioNxt Advances GLP-1 Sublingual Semaglutide

*adapted from American Diabetes Association 2024 Standards of Care in Diabetes Available GLP-1 Receptor Agonists (GLP-1 RA) The Table below compares currently available GLP-1RA formulations, notes on their dosing and administration schedule, adjustments and demonstrated cardiorenal benefits

Unlike the weight-loss medications mentioned above which require daily or weekly injections, the Allurion Balloon is a non-surgical weight-loss tool

doi: 10.1210/endocr/bqab020 192 ZhangLFernandoTLiuYLiuYZhuXLiMet al

doi: 10.1210/en.2013-1934 193 PanjwaniNMulvihillEELonguetCYustaBCampbellJEBrownTJet al

The portal is available on both desktop and mobile browsers