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Effects of liraglutide in the treatment of obesity: a randomized, double-blind, placebo-controlled study

Neither compound showed unexpected serious adverse events in isolation during clinical trials lasting up to 48 weeks

Additionally, GLP-1 activation affects the chemoreceptor trigger zone in your brain, which controls the nausea responsea normal part of how the drug signals your system to eat less

However, it was never intended to be a mass-market substitute for FDA-approved, patented medications

Metformin use may be associated with lower risks of cardiac allograft vasculopathy after heart transplantation (288) and all-cause, malignancy-related, and infection-related mortality after kidney transplantation (289)