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Genetically-predicted GLP1R expression (the target of GLP-1 RAs) showed an inverse association with background [odds ratio (OR)=0.83, 95% CI, 0.710.97] and severe nonproliferative DR (OR=0.72, 95% CI, 0.530.98), and a non-significant association with overall (OR=0.97, 95% CI, 0.921.03) and proliferative DR (OR=0.98, 95% CI, 0.911.05)

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These are found in fish and shellfish and are great allies for endothelial function and as anti-inflammatories

TZP is currently used as a second-line treatment option for diabetes management, much as GLP-1 receptor agonists like semaglutide