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Postmarketing surveillance and observational studies have reported cases of pancreatitis in patients receiving GLP-1 receptor agonists, although a causal relationship remains debated and confounded by underlying disease risk factors ( In addition, rodent studies demonstrating thyroid C-cell hyperplasia and tumors led to class warnings and contraindications in susceptible populations

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He added that the GLP-1 shortages feel like a "national health-care crisis." "I don't think that people are fully registering that lifesaving and life-altering medications that could benefit well over 100 million people in the U.S

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