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[DOI] [PMC free article] [PubMed] [Google Scholar] 115.Joseph A., Thuy T.T.T., Thanh L.T., Okada M

Reserve stimulant laxatives for situations where these measures fail after 48-72 hours

Perhaps more importantly for tolerability, GIP activation seems to buffer against the nausea commonly caused by GLP-1 stimulation alone

Medication-interaction guidance: not confirmed from a label - ask a doctor or pharmacist before use if you're on any prescription medication

Rotate sites weekly to reduce irritation and improve absorption
