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Because GLP-2 acts through subepithelial myofibroblasts, which are the same cell population implicated in intestinal fibrogenesis, the risk-benefit profile of GLP-2 agonism may differ substantially between mucosal UC, inflammatory ileal CD, and stricturing or penetrating CD phenotypes, and this phenotypic stratification should be a required feature of future trial design
81 Similarly, Chien et al

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The base effect: why expected widening amplifies the signal A third of the savings made on food by users of GLP-1 medications are being redirected to other health and wellness categories (clothing, wellness products), according to analysts cited by LinkedIn
