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95% CI, 0.77-0.87), and ESKD (HR, 0.61

Metallothionein is downstream of nrf2 and partially mediates sulforaphane prevention of diabetic cardiomyopathy

Conversely, brain serotonin depletion leads to hyperphagia and obesity (7, 8), though this effect is not always replicated (9, 10)

CI poses a significant burden on older patients diagnosed with type-2 diabetes, substantially impacting their quality of life and overall health outcomes [1, 2]