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Description
SGLT2 inhibitors have been associated with improved cardiovascular outcomes, not only through their immediate hemodynamic effectssuch as glycosuria and (at least temporary) increased natriuresisbut also due to their multifaceted impact on metabolism

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Berberine further improves hepatic detoxification efficiency, significantly reduces lipid accumulation, and stabilizes mitochondrial function
Gastrointestinal symptoms were the most common side effects

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