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These agents were initially developed for managing type 2 diabetes (T2DM) but now are proven to be remarkably effective weight loss drugs (Table 1) [47, 48, 49, 50]
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Impact of canagliflozin on kidney and cardiovascular outcomes by type 2 diabetes duration: a pooled analysis of the CANVAS program and CREDENCE trials
A low-fibre diet has historically been associated with increased risk, as it may lead to harder stools and increased pressure within the colon during bowel movements
