on glp 1 and not losing weight Are YOU a Slow/Non-Responder to GLP-1's? Why Am I Not Losing

The Swedish Obese Subjects study supported this, finding that modest weight loss of 5 kg was not enough to alter CVD risk, whereas 1044 kg weight loss in the setting of bariatric surgery was needed for significant risk factor reduction at 10-year follow-up [98]

Similarly, Inzucchi et al [27] believed that the evidence of GLP-1 receptor agonist cardiovascular protection was still limited, and the cardiovascular system benefits related to GLP-1 receptor agonists may be independent of its glucose, lipid, or energy metabolism effects

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Common side effects include nausea, vomiting, constipation, and appetite changes

Following this spike, switching rates declined after the spike but stayed elevated (~1.6%) through September before returning to baseline in October 2025