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Their BMI decreased by 3kg/m2, on average, over 12 months

The primary outcome was similar between two groups in the IVT-stratum

In December 2025, Eli Lilly published the first positive Phase 3 readout for retatrutide (LY3437943), the triple-agonist peptide that had, until then, only been validated at Phase 2 scale

Maybe you're concerned about potential "withdrawal symptoms," weight regain, or changes in your blood sugar levels

In everyday clinical practice, a combination of different strategies, for example, diet with metformin and statins, is very common, considering that it is the treatment indicated for the conditions which are causally linked to the pathogenesis of NAFLD/NASH