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Sci Transl Med 16(778):eadp5765

The semaglutide and kidney stones guide and semaglutide and liver enzymes article address organ-level considerations

Quick Answer: Most people notice appetite suppression within days to two weeks of starting GLP-1 treatment, blood glucose improvements within 24 weeks, and meaningful weight loss over 36 months

The agency's warnings about unapproved ingredients and quality control failures underscore the need for vigilance from prescribers

This adjustment period usually resolves within 24 weeks as cardiovascular fitness improves with the new body composition
