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This review examines the biological mechanisms underlying GLP-1 RA therapy in MASLD/MASH, analyzes the mechanistic distinctions between mono-, dual-, and triple agonists, and synthesizes current clinical evidence supporting their utilization in individuals with this condition.

Albert, MBA, PharmD, JD, DASPL

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As the use of these agents continues to expand, perioperative clinicians are increasingly encountering patients receiving medications such as semaglutide, liraglutide, dulaglutide, and tirzepatide before surgical and procedural interventions

What it means for you If you have diabetes or obesity and are prescribed a GLP-1 RA anyway, it may be a potential added brain-health benefitbut not a guarantee